CARDIOVASCULAR EXERCISE IMPROVES WOMEN’S HEART HEALTH

Heart disease kills millions of Americans each year. It is the leading cause of death for both men and women. The most common heart disease in the United States is coronary artery disease (CAD), which leads to heart attacks. One way to reduce your risk of CAD is to make some lifestyle changes, such as healthy eating, stress management and physical activity.   Physical activity is an essential part of being heart healthy. The American Heart Association (AHA) says you need at least 150 minutes of moderate....

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LATEST BREAKTHROUGHS IN BREAST CANCER TREATMENT

There are an estimated 2.8 million breast cancer survivors in the United States, a testament to the more than 25-year decline in mortality, according to the American Cancer Society. Still, 231,000 women will be diagnosed with the disease this year, and about 40,000 will die. Fortunately, there have been some exciting breakthroughs in breast cancer detection and treatment recently.

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PERSONAL TRAINING

If you’re looking for a safe, effective program that will help you get toned, become more flexible or lose weight, personal training could be for you.  A personal trainer will teach you proper form and technique to keep you safe and injury free. But first, he or she needs to know what your goals are – whether you want to lose weight, get healthy and tone up or train for bodybuilding, fitness competitions or powerlifting. Perhaps you’re an older person who wants to work on balance and stability.

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Better understanding of the type of depression a person experiences couldi mprove the effectiveness of treatment choices and the management of depressive symptoms. Depression is typically diagnosed based on verbalized symptoms patients experience. This relates to the way the symptoms are assessed and the accuracy of patient reporting.


Conor Liston, M.D., a professor of neuroscience and psychiatry at Weill Cornell Medicine in New York, reports his research team, using brain scans, has identified four unique subtypes of clinical depression based on distinct patterns of abnormal brain connectivity. Their findings appear currently in Nature Medicine (December 2016).


“The four subtypes of depression that we discovered vary in terms of their clinical symptoms but, more importantly, they differ in their responses to treatment,” said Liston. For psychiatric care and treatment, using brain scans may assist mental health professionals in understanding the nature of a patient’s depression.


This collaborative study included 1,180 functional magnetic resonance imaging (fMRI) brain scans of patients with clinical depression and healthy controls from across the country. Researchers from Weill Cornell Medicine and seven other institutions analyzed the scans and identified biomarkers linked with depression by assigning statistical weights

CURRENT RESEARCH REVEALS FOUR DEPRESSION SUBTYPES

to abnormal brain connections. They then predicted the probability the abnormal connections belonged to a particular subtype versus another. The study showed distinct patterns of abnormal connectivity in the brain differentiated among the four subtypes and were linked with specific symptoms. Reduced connectivity in the brain region that regulates fear-related behavior and reappraisal of negative emotional stimuli, for example, was most severe in two of the four subtypes, which demonstrated increased anxiety. The researchers believe their findings may be useful for identifying patients most likely to benefit from targeted neuro-stimulation therapies. In the past, efforts to characterize depression by looking at groups of verbalized symptoms that tend to co-occur and then testing neurophysiological links have produced inconsistent results.


Sources and Resources:


•  Drysdale, A.T., Grosenick, L., Downar, J., et al. (2016) Resting-state connectivity biomarkers define neurophysiological subtypes of depression. Nature Medicine, 2016 December 5.

•  Neuroimaging categorizes for depression subtypes. Weill Cornell Medicine press release, Dec. 5, 2016.

DR. THOMAS W. MILLER, PH.D, ABPP

Thomas W. Miller, Ph.D., ABPP, is a professor emeritus and senior research scientist, Center for Health, Intervention and Prevention, University of Connecticut; retired service chief from the VA Medical Center; and tenured professor in the Department of Psychiatry, College of Medicine, University of Kentucky.

more articles by Dr thomas w. miller