GOING GLUTEN-FREE

Gluten is a particular kind of protein that is not found in eggs or meat but is in barley, rye, wheat and triticale (a cross between wheat and rye). Going gluten-free means avoiding these grains. A gluten-free diet is essential for those who have celiac disease, a condition that causes inflammation in the small intestines, or gluten allergies.  Symptoms of celiac disease include anemia, constipation or diarrhea, bloating, gas, headaches, skin rashes, joint pain and fatigue.

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A DIET FOR HEALTH & WEIGHT LOSS

Have you noticed? Look around and you’ll see a majority of Americans who are either overweight or obese. Look in supermarkets and you’ll see a plethora of food products, many of them processed or high-fat and/or sweet laden.  Consuming such a diet often leads to poor health and weight gain. It is not surprising that the leading cause of death in the United States is heart disease. A number of diseases, including pre-diabetes, diabetes, stroke and depression, are linked to how we eat .....

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ANTIBIOTICS IN OUR FOOD

Just what is in the food we eat? Considering the food chain, did you know adding antibiotics to food dates back to the 1940s? Antibiotic use has led to a dramatic reduction in illness and death from infectious diseases, yet there is a downside to this practice. The Centers for Disease Control and Prevention (CDC) and others encourage health care professionals and patients to use antibiotics more wisely and seek education and understanding about both the risks and benefits of using them.

….FULL ARTICLE

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Better understanding of the type of depression a person experiences couldi mprove the effectiveness of treatment choices and the management of depressive symptoms. Depression is typically diagnosed based on verbalized symptoms patients experience. This relates to the way the symptoms are assessed and the accuracy of patient reporting.


Conor Liston, M.D., a professor of neuroscience and psychiatry at Weill Cornell Medicine in New York, reports his research team, using brain scans, has identified four unique subtypes of clinical depression based on distinct patterns of abnormal brain connectivity. Their findings appear currently in Nature Medicine (December 2016).


“The four subtypes of depression that we discovered vary in terms of their clinical symptoms but, more importantly, they differ in their responses to treatment,” said Liston. For psychiatric care and treatment, using brain scans may assist mental health professionals in understanding the nature of a patient’s depression.


This collaborative study included 1,180 functional magnetic resonance imaging (fMRI) brain scans of patients with clinical depression and healthy controls from across the country. Researchers from Weill Cornell Medicine and seven other institutions analyzed the scans and identified biomarkers linked with depression by assigning statistical weights

CURRENT RESEARCH REVEALS FOUR DEPRESSION SUBTYPES

to abnormal brain connections. They then predicted the probability the abnormal connections belonged to a particular subtype versus another. The study showed distinct patterns of abnormal connectivity in the brain differentiated among the four subtypes and were linked with specific symptoms. Reduced connectivity in the brain region that regulates fear-related behavior and reappraisal of negative emotional stimuli, for example, was most severe in two of the four subtypes, which demonstrated increased anxiety. The researchers believe their findings may be useful for identifying patients most likely to benefit from targeted neuro-stimulation therapies. In the past, efforts to characterize depression by looking at groups of verbalized symptoms that tend to co-occur and then testing neurophysiological links have produced inconsistent results.


Sources and Resources:


•  Drysdale, A.T., Grosenick, L., Downar, J., et al. (2016) Resting-state connectivity biomarkers define neurophysiological subtypes of depression. Nature Medicine, 2016 December 5.

•  Neuroimaging categorizes for depression subtypes. Weill Cornell Medicine press release, Dec. 5, 2016.

DR. THOMAS W. MILLER, PH.D, ABPP

Thomas W. Miller, Ph.D., ABPP, is a professor emeritus and senior research scientist, Center for Health, Intervention and Prevention, University of Connecticut; retired service chief from the VA Medical Center; and tenured professor in the Department of Psychiatry, College of Medicine, University of Kentucky.

more articles by Dr thomas w. miller